Medium Chain Triglycerides, or MCTs, Can Help Recharge The Brain’s Metabolic Processes
How can a few tablespoons of Medium Chain Triglycerides produce an almost instant improvement in the cognitive performance of older adults with cognitive impairments such as Alzheimers?
Unlike the majority of fats we consume, MCTs are not stored as fat by the body and can be used to produce ketone bodies, which the brain can use as a source of fuel.
Not only does coconut oil help with memory and other cognitive functions, it has many other health benefits as well, which you will learn about in this article.
Medium Chain Triglycerides (MCTs), the primary type of fat found within coconut oil, have been found to boost cognitive performance in older adults suffering from memory disorders as serious as Alzheimer’s — and not after months or even days of treatment, but after a single 40 ml dose!
A groundbreaking 2004 study published in the journal Neurobiology of Aging found that the administration of medium chain triglycerides (MCTs), the primary fat type found in coconut oil, almost immediately improved cognitive function in older adults with memory disorders.
The study involved 20 subjects with Alzheimer’s disease or mild cognitive impairment who, on separate days, were given either emulsified MCTs or a placebo. The researchers observed a significant increase in blood plasma levels of the ketone body beta-hydroxylutyrate (beta-OHB) after only 90 minutes of treatment, and depending on the apolipoprotein E genotype of the subject tested, beta-OHB levels either continued to rise or held constant between the 90 and 120 minute blood draws in the treatment condition. Remarkably, cognitive testing revealed that this brief MCT treatment facilitated improved performance on the Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-cog) in 4 subjects within the study group. Moreover, “higher ketone values were associated with greater improvement in paragraph recall with MCT treatment relative to placebo across all subjects (P=0.02).”[i]
How Medium Chain Triglycerides Work
How could a single dose of MCTs (40 ml or 2.7 tablespoons) cause an almost immediate improvement in cognitive performance in those suffering from cognitive impairments as serious as Alzheimer’s disease? The explanation is found both in the unique metabolic needs of the brain and in the configuration of MCTs themselves. Whereas the primary fuel source for the energy-hungry brain is glucose, when insulin resistance and suboptimal metabolism (hypometabolism) develops in the brain, both the brain’s structure and function are compromised. Ketone bodies provide a much needed alternative fuel source to glucose that can recharge metabolic processes within the brain, resulting in an almost immediate improvement in cognitive function.
MCTs are not like most fats we consume. For instance, due to their smaller size they do not form micelles and are not stored in adipose tissue. Whereas up to 97% of the dietary fats we ingest are made up of long-chain triglycerides (LCTs) which have been 14 and 18 carbons,[ii] MCTs have relatively shorter chain lengths of 5 to 12 carbons, making them easier to absorb and utilize. They are preferentially oxidized by the liver, and when provided in large enough quantities, they give rise to ketone bodies.[iii]
Also, instead of treating coconut oil…….
Written by Sayer Ji, GreenMedInfo, where this article was originally published